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1

Bicarbonate/lactate-based peritoneal dialysis solution increases cancer antigen 125 and decreases hyaluronic acid levels

Jones, Suzanne, Holmes, Clifford J., Krediet, Raymond T., Mackenzie, Ruth, Faict, Dirk, Tranaeus, Anders, Williams, John D., Coles, Gerald A., Topley, Nicholas

Journal:

Kidney International

Année:

2001

Langue:

english

Fichier:

PDF, 409 KB

english, 2001

2

The Euro-Balance Trial: The effect of a new biocompatible peritoneal dialysis fluid (balance) on the peritoneal membrane

Williams, John D., Topley, Nicholas, Craig, Kathrine J., Mackenzie, Ruth K., Pischetsrieder, Monika, Lage, Cristina, Passlick-Deetjen, Jutta

Journal:

Kidney International

Année:

2004

Langue:

english

Fichier:

PDF, 157 KB

english, 2004

3

In vivo exposure to bicarbonate/lactate- and bicarbonate-buffered peritoneal dialysis fluids improves ex vivo peritoneal macrophage function

Ruth K. Mackenzie, Suzanne Jones, Andrew Moseley, Clifford J. Holmes, Ruth Argyle, John D. Williams, Gerald A. Coles, Kewei Pu, Dirk Faict, Nicholas Topley

Journal:

American Journal of Kidney Diseases

Année:

2000

Langue:

english

Fichier:

PDF, 72 KB

english, 2000

4

Encapsulating Peritoneal Sclerosis: Definition, Etiology, Diagnosis, and Treatment

Kawaguchi, Yoshindo, Kawanishi, Hideki, Mujais, Salim, Topley, Nicholas, Oreopoulos, Dimitrios G.

Journal:

Peritoneal Dialysis International

Année:

2000

Fichier:

PDF, 99 KB

2000

5

Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis

Peter J. Richards, Mari A. Nowell, Sankichi Horiuchi, Rachel M. McLoughlin, Ceri A. Fielding, Sandra Grau, Naoki Yamamoto, Michael Ehrmann, Stefan Rose-John, Anwen S. Williams, Nicholas Topley, Simon

Journal:

Arthritis & Rheumatism

Année:

2006

Langue:

english

Fichier:

PDF, 867 KB

english, 2006

6

Interferon-γ protects against the development of structural damage in experimental arthritis by regulating polymorphonuclear neutrophil influx into diseased joints

Anwen S. Williams, Peter J. Richards, Eleri Thomas, Sara Carty, Mari A. Nowell, Rhian M. Goodfellow, Colin M. Dent, Bryan D. Williams, Simon A. Jones, Nicholas Topley

Journal:

Arthritis & Rheumatism

Année:

2007

Langue:

english

Fichier:

PDF, 443 KB

english, 2007

7

Factors affecting the measurement of chemiluminescence in stimulated human polymorphonuclear leucocytes

Michael J. Harber, Nicholas Topley

Journal:

Année:

1986

Langue:

english

Fichier:

PDF, 1.03 MB

english, 1986

8

TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2

Anne-Catherine Raby, Benjamin Holst, James Davies, Chantal Colmont, Yves Laumonnier, Barbara Coles, Sanjoy Shah, Judith Hall, Nicholas Topley, Jörg Köhl, B. Paul Morgan, Mario O. Labéta

Journal:

European Journal of Immunology

Année:

2011

Langue:

english

Fichier:

PDF, 349 KB

english, 2011

9

Introduction

Topley, Nicholas, Lameire, Norbert, Jörres, Achim, Winney, Robin, Williams, John D

Journal:

Kidney International

Année:

1998

Langue:

english

Fichier:

PDF, 57 KB

english, 1998

10

Leukocyte migration across human peritoneal mesothelial cells is dependent on directed chemokine secretion and ICAM-1 expression

Li, Fu Keung, Davenport, Andrew, Robson, Rachel L, Loetscher, Pius, Rothlein, Robert, Williams, John D, Topley, Nicholas

Journal:

Kidney International

Année:

1998

Langue:

english

Fichier:

PDF, 727 KB

english, 1998

11

Glucose degradation products (GDP) retard remesothelialization independently of d-glucose concentration

Morgan, Llinos W., Wieslander, Anders, Davies, Malcolm, Horiuchi, Takashi, Ohta, Yuji, Beavis, M. Janine, Craig, Kathryn J., Williams, John D., Topley, Nicholas

Journal:

Kidney International

Année:

2003

Langue:

english

Fichier:

PDF, 10.90 MB

english, 2003

12

Glucose-mediated induction of TGF-β1 and MCP-1 in mesothelial cells in vitro is osmolality and polyol pathway dependent

Wong, Teresa YH, Phillips, Aled O, Witowski, Janusz, Topley, Nicholas

Journal:

Kidney International

Année:

2003

Langue:

english

Fichier:

PDF, 2.47 MB

english, 2003

13

Clinical indices of in vivo biocompatibility: The role of ex vivo cell function studies and effluent markers in peritoneal dialysis patients

Mackenzie, Ruth, Holmes, Clifford J., Jones, Suzanne, Williams, John D., Topley, Nicholas

Journal:

Kidney International

Année:

2003

Langue:

english

Fichier:

PDF, 192 KB

english, 2003

14

The in vitro biocompatibility performance of a 25 mmol/L bicarbonate/10 mmol/L lactate-buffered peritoneal dialysis fluid

Skoufos, Line, Topley, Nicholas, Cooker, Laurinda, Dawnay, Anne, Millar, David J., Holmes, Clifford J., Faict, Dirk

Journal:

Kidney International

Année:

2003

Langue:

english

Fichier:

PDF, 88 KB

english, 2003

15

The natural course of peritoneal membrane biology during peritoneal dialysis

Williams, John D., Craig, Kathrine J., Ruhland, Chris von, Topley, Nicholas, Williams, Geraint T

Journal:

Kidney International

Année:

2003

Langue:

english

Fichier:

PDF, 136 KB

english, 2003

16

Peritoneal dialysis: Changes to the structure of the peritoneal membrane and potential for biocompatible solutions

Williams, John D., Craig, Kathrine J., Topley, Nicholas, Williams, Geraint T.

Journal:

Kidney International

Année:

2003

Langue:

english

Fichier:

PDF, 241 KB

english, 2003

17

Modulation of Interleukin-8-Mediated Neutrophil Migration Following Major Lower-Limb Fracture and Operative Stabilization

Raj Bhatia, Colin Dent, Nicholas Topley, Ian Pallister

Journal:

European Journal of Trauma and Emergency Surgery

Année:

2005

Langue:

english

Fichier:

PDF, 409 KB

english, 2005

18

Peritoneal defence in peritoneal dialysis

NICHOLAS TOPLEY, ANDREW DAVENPORT, FU-KEUNG LI, HUW FEAR, JOHN D WILLIAMS

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 536 KB

english, 1996

19

Reply from the Authors

WILLIAMS, JOHN D, CRAIG, KATHRINE J, VON RUHLAND, CHRIS, TOPLEY, NICHOLAS, WILLIAMS, GERAINT T

Journal:

Kidney International

Année:

2004

Langue:

english

Fichier:

PDF, 46 KB

english, 2004

20

Neutrophil activation and renal scarring

Topley, Nicholas, Steadman, Robert, Williams, John D.

Journal:

Kidney International

Année:

2005

Langue:

english

Fichier:

PDF, 38 KB

english, 2005

21

The effect of dialysate on peritoneal phagocyte oxidative metabolism

Topley, Nicholas, Alobaidi, Haifa M M, Davies, Malcolm, Coles, Gerald A, Williams, John D, Lloyd, David

Journal:

Kidney International

Année:

1988

Langue:

english

Fichier:

PDF, 789 KB

english, 1988

22

Interleukin 1-α and tumor necrosis factor-α induce oxygen radical production in mesangial cells

Topley, Nicholas, Flöge, Jürgen, Habermehl, Gerhard G, Resch, Klaus, Radeke, Heinfried H, Meier, Beate

Journal:

Kidney International

Année:

1990

Langue:

english

Fichier:

PDF, 873 KB

english, 1990

23

Activation of the inflammatory response of neutrophils by Tamm-Horsfall glycoprotein

Horton, Jeffrey K, Davies, Malcolm, Topley, Nicholas, Thomas, David, Williams, John D

Journal:

Kidney International

Année:

1990

Langue:

english

Fichier:

PDF, 923 KB

english, 1990

24

Monokines and platelet-derived growth factor modulate prostanoid production in growth arrested, human mesangial cells

Floege, Jürgen, Topley, Nicholas, Wessel, Klaus, Kaever, Volkhard, Radeke, Heinfried, Hoppe, Jürgen, Kishimoto, Tadamitsu, Resch, Klaus

Journal:

Kidney International

Année:

1990

Langue:

english

Fichier:

PDF, 1.09 MB

english, 1990

25

Human peritoneal mesothelial cells synthesize interleukin-6: Induction by IL-1β and TNFα

Topley, Nicholas, Jörres, Achim, Luttmann, Werner, Petersen, Meryl M, Lang, M Janine, Thierauch, Karl-Heinz, Müller, Christian, Coles, Gerald A, Davies, Malcolm, Williams, John D

Journal:

Kidney International

Année:

1993

Langue:

english

Fichier:

PDF, 914 KB

english, 1993

26

Oxidation of low density lipoprotein by mesangial cells may promote glomerular injury

Wheeler, David C, Chana, Ravinder S, Topley, Nicholas, Petersen, Meryl M, Davies, Malcolm, Williams, John D

Journal:

Kidney International

Année:

1994

Langue:

english

Fichier:

PDF, 969 KB

english, 1994

27

Human peritoneal mesothelial cell prostaglandin synthesis: Induction of cyclooxygenase mRNA by peritoneal macrophage-derived cytokines

Topley, Nicholas, Petersen, Meryl M, Mackenzie, Ruth, Neubauer, Andreas, Stylianou, Eleni, Kaever, Volkard, Davies, Malcolm, Coles, Gerald A, Jörres, Achim, Williams, John D

Journal:

Kidney International

Année:

1994

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1994

28

Effect of lactate-buffered peritoneal dialysis fluids on human peritoneal mesothelial cell interleukin-6 and prostaglandin synthesis

Witowski, Janusz, Topley, Nicholas, Jörres, Achim, Liberek, Tomasz, Coles, Gerald A, Williams, John D

Journal:

Kidney International

Année:

1995

Langue:

english

Fichier:

PDF, 1.37 MB

english, 1995

29

Biocompatibility of bicarbonate buffered peritoneal dialysis fluids: Influence on mesothelial cell and neutrophil function

Topley, Nicholas, Kaur, Davender, Petersen, Meryl M, Jörres, Achim, Passlick-Deetjen, Jutta, Coles, Gerald A, Williams, John D

Journal:

Kidney International

Année:

1996

Langue:

english

Fichier:

PDF, 1.07 MB

english, 1996

30

Superinduction of IL-6 synthesis in human peritoneal mesothelial cells is related to the induction and stabilization of IL-6 mRNA

Witowski, Janusz, Jörres, Achim, Coles, Gerald A, Williams, John D, Topley, Nicholas

Journal:

Kidney International

Année:

1996

Langue:

english

Fichier:

PDF, 1.47 MB

english, 1996

31

Induction of TGF-β1 synthesis in D-glucose primed human proximal tubular cells by IL-1β and TNFα

Phillips, Aled O, Topley, Nicholas, Steadman, Robert, Morrisey, Kimberley, Williams, John D

Journal:

Kidney International

Année:

1996

Langue:

english

Fichier:

PDF, 912 KB

english, 1996

32

Longitudinal evaluation of peritoneal macrophage function and activation during CAPD: Maturity, cytokine synthesis and arachidonic acid metabolism

McGregor, Sheila J, Topley, Nicholas, Jörres, Achim, Speekenbrink, Antony B J, Gordon, Anne, Gahl, Gerhard M, Junor, Brian J R, Briggs, J Douglas, Brock, Jeremy H

Journal:

Kidney International

Année:

1996

Langue:

english

Fichier:

PDF, 724 KB

english, 1996

33

Human peritoneal fibroblast proliferation in 3-dimensional culture: Modulation by cytokines, growth factors and peritoneal dialysis effluent

Beavis, M Janine, Williams, John D, Hoppe, Jürgen, Topley, Nicholas

Journal:

Kidney International

Année:

1997

Langue:

english

Fichier:

PDF, 1.26 MB

english, 1997

34

Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-β signaling

Jenkins, Brendan J, Grail, Dianne, Nheu, Thao, Najdovska, Meri, Wang, Bo, Waring, Paul, Inglese, Melissa, McLoughlin, Rachel M, Jones, Simon A, Topley, Nicholas

Journal:

Nature Medicine

Année:

2005

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2005

35

Early Peritoneal Responses to Bacterial Invasion: Cellular Exudation

Andrew Davenport, Fu-Keung Li, Rachel Robson, Thomas S Wilkinson, Rachel McLoughlin, Nicholas Topley

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 98 KB

english, 1999

36

Regulation of TNF-α, IL-1 and IL-6 synthesis in differentiating human monoblastoid leukemic U937 cells

Ralf Hass, Gerhard Lonnemann, Daniela Mannel, Nicholas Topley, Andreas Hartmann, Lars Köhler, Klaus Resch, Margarete Goppelt-Strübe

Journal:

Leukemia Research

Année:

1991

Langue:

english

Fichier:

PDF, 1.61 MB

english, 1991

37

Enhanced neutrophil migratory activity following major blunt trauma

Raj K. Bhatia, Ian Pallister, Colin Dent, Simon A. Jones, Nicholas Topley

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 200 KB

english, 2005

38

Staphylococcal exoproducts down-regulate cyclooxygenase 1 and 2 in peritoneal macrophages

Ruth K. Mackenzie, Nicholas Topley, Andreas Neubauer, Gerald A. Coles, John D. Williams

Journal:

Journal of Laboratory and Clinical Medicine

Année:

1997

Langue:

english

Fichier:

PDF, 2.45 MB

english, 1997

39

INHIBITION OF TUMOUR NECROSIS FACTOR PRODUCTION IN ENDOTOXIN-STIMULATED HUMAN MONONUCLEAR LEUKOCYTES BY THE PROSTACYCLIN ANALOGUE ILOPROST: CELLULAR MECHANISMS

Achim Jörres, Harald Dinter, Nicholas Topley, Gerhard M. Gahl, Ulrich Frei, Peter Scholz

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 297 KB

english, 1997

40

48 Oncostatin M Receptor Signalling Regulates Monocytic Cell Trafficking during Acute Inflammation

Emily Hams, Vincent Dioszechy, Chantal Colmont, Victoria Hammond, Ceri Fielding, Anwen S. Williams, Minoru Tanaka, Atsushi Miyajima, Philip R. Taylor, Nicholas Topley, Simon A. Jones

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 48 KB

english, 2007

41

66 TL1A Counteracts the IL-6 Control of the STAT3-Mediated Development of T Helper 17 Cells

Gareth W. Jones, Zarabeth Mecklenburgh, Brendan J. Jenkins, Matthias Ernst, Nicholas Topley, Anwen S. Williams, Eddie Wang, Simon A. Jones

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 65 KB

english, 2007

42

47 The Role of Interleukin-6 in Monocyte Activation and Trafficking

Victoria Hammond, Vincent Dioszeghy, Chantal Colmont, Emily Hams, Gareth Jones, Nicholas Topley, Phil Taylor, Valerie O’Donnell, Simon A. Jones

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 62 KB

english, 2007

43

37 PMN Recruitment is Regulated by GP130-Mediated Stat Activation

Ceri A. Fielding, Rachel M. McLoughlin, Louise McLeod, Chantal S. Colmont, Dianne Grail, Meri Najdovska, Mathias Ernst, Simon A. Jones, Nicholas Topley, Brendan J. Jenkins

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 47 KB

english, 2007

44

28 Differential roles of IL-6 and IL-11 in inflammation and tumorigenesis

Brendan J. Jenkins, Meri Nadjovska, Claire Greenhill, Louise McLeod, Hazel Tye, Catherine Kennedy, Ceri Fielding, Nicholas Topley, Simon A. Jones, Matthias Ernst, Paul J. Hertzog

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 120 KB

english, 2008

45

49 Regulation of TLR mediated responses in the peritoneal cavity

Chantal S. Colmont, Mario O. Labéta, Anne-Catherine Raby, Barbara Coles, Simon A. Jones, Nicholas Topley

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 44 KB

english, 2008

46

121 Differential control of T-cell responses by classical IL-6 receptor signaling and IL-6 trans-signaling

Gareth W. Jones, Rachel M. McLoughlin, Victoria J. Hammond, Clare R. Parker, John D. Williams, Raj Malhotra, Jürgen Scheller, Stefan Rose-John, Nicholas Topley, Simon A. Jones

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 51 KB

english, 2008

47

264 The inflammatory trafficking of monocytic cells in IL-6-deficient mice highlights the emergence of a CD11c+ monocytic population

Victoria J. Hammond, Vincent Dioszeghy, Chantal Colmont, Emily Hams, Gareth W. Jones, Nicholas Topley, Valerie O’Donnell, Philip R. Taylor, Simon A. Jones

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 120 KB

english, 2008

48

Loss of T-cell IL-6R expression during inflammation: IL-6 trans-signaling regulates T-cell trafficking and effector characteristics

Gareth W. Jones, Rachel M. McLoughlin, Victoria J. Hammond, Clare R. Parker, John D. Williams, Raj Malhotra, Jürgen Scheller, Stefan Rose-John, Nicholas Topley, Simon A. Jones

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 63 KB

english, 2009

49

SS11-4 Local manipulation of IL-6 trans-signaling therapeutically enhances anti-microbial host defense

Barbara Coles, Chantal Colmont, Ceri A. Fielding, Ann Kift-Morgan, Emily Hams, Nicholas Topley, Simon A. Jones

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 146 KB

english, 2010

50

CHAPTER 12 - Macrophages and Mesothelial Cells in Bacterial Peritonitis

Nicholas Topley, Ruth K. Mackenzie, John D. Williams

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 1.05 MB

english, 1996